表皮生长因子（EGF） 蛋白, Human

产品包装规格：

种属：              Human Cells

表达系统：      Prokaryotic expression system、Eukaryotic expression system 

标签：              not have  

同用名：          EGF; Pro-epidermal growth factor; Epidermal growth factor
分子量：          19.6 KDa

纯度：              Purity: ≥97% (SDS-PAGE)

储存条件：       -20℃

备注：             avoid repeated freeze/thaw cycles
                     
储存时间：      The product should be stored at -20°C and will remain active for up to two years.
                         After resuspension, it can be stored at 2 to -8 °C for one month,
                         or at -70 to -20 °C for longer periods

运输：             The product is shipped at -20°C.
                      

背景：            Epidermal Growth Factor (EGF) is a small mitogenic polypeptide (~6 kDa) which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids.1 Human EGF is identical to b-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion.2 EGF is a member of a growth factor family which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF.3 EGF is structurally homologous to human transforming growth factor-a (TGF-a), and both exert their actions through EGF receptors.4 EGF is homologous to a sequence contained in a 19 kD protein of vaccinia virus,5 which appears to utilize the EGF receptor to gain entry into cells.6 EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells. 

样品信息：

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